A delegation consisting of 50 people including merchants and Thai companies' officials accompany the Foreign Minister.
Pramudwinai will first visit his counterpart Mohammad Javad Zarif.
Currently, Iran owns only a $99m-share of $200b-Thai market.
In the wake of lifting anti-Iran sanctions, Iranian merchants have an eye on Thai's markets to export their products.
Iranian companies also tend to participate in Thailand's infrastructural plans.